Transplantation of cells for cardiac repair
نویسندگان
چکیده
منابع مشابه
Cell transplantation for cardiac repair.
Despite remarkable progress in contemporary cardiovascular therapy, treatment of heart failure still remains a therapeutic challenge. Pharmacological treatment using -blockers, angiotensin converting enzyme inhibitors, and angiotensin-II receptor blockers, as well as surgical revascularization together with left ventricular reshaping procedures, has improved the quality of life for heart failur...
متن کاملTherapeutic angiogenesis promotes efficacy of human umbilical cord matrix stem cell transplantation in cardiac repair
Objective(s):Although previous studies have confirmed the beneficial effects of human umbilical cord matrix stem cell (hUCM) transplantation post myocardial infarction (MI), but this stem cell resource has no potential to induce angiogenesis. In order to achieve the process of angiogenesis and cardiomyocyte regeneration, two required factors for cardiac repair agents were examined namely; hUCM ...
متن کاملDonor mitral valve repair in cardiac transplantation.
INTRODUCTION For many patients suffering from end-stage heart failure, heart transplantation remains the only hope for survival, but the shortage of donor organ is increasing. The growing number of patients awaiting heart transplantation has led many centers to expand the donor pool by liberalizing donor criteria, including advances in surgical techniques on the donor heart, such as valve repai...
متن کاملBone marrow stem cell transplantation for cardiac repair.
Cardiomyocytes respond to physiological or pathological stress only by hypertrophy and not by an increase in the number of functioning cardiomyocytes. However, recent evidence suggests that adult cardiomyocytes have the ability, albeit limited, to divide to compensate for the cardiomyocyte loss in the event of myocardial injury. Similarly, the presence of stem cells in the myocardium is a good ...
متن کاملMyoblast Transplantation for Cardiac Repair Using Transient Immunosuppression
Myoblast transplant for cardiac repair offers an alternative therapeutic modality for cardiac repair. This novel cell based approach has the potential for replacing cardiomyocytes damaged during the disease process. Studies in the small and large animals and human phase-I trials have shown that myoblast transplantation into damaged myocardium results in the improved myocardial function and hemo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2003
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(02)02933-9